Practical Events in the Management of a Collodion Baby.

نویسندگان

  • Michelle A Nguyen
  • Ari Gelman
  • Scott A Norton
چکیده

In our series, all patients had quick good-quality remissionwith amedianprogression-free survival of 6months. The rapidity of the response supports the role of vinblastine instead of spontaneous regression in these patientswithmultifocal lesions and a long-term history of refractory disease. In our series, no patient had to discontinue use of the drug because of infection or severe toxic effects. Vinblastine should be studied in larger series to confirm its effectiveness and tolerance in disseminated or refractory C-ALCL. Its place as second-line treatment could be consideredwith failureofmethotrexateandperhapsas first-line treatment in the case of contraindication to methotrexate, especially in older adults.

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عنوان ژورنال:
  • JAMA dermatology

دوره 151 9  شماره 

صفحات  -

تاریخ انتشار 2015